New developments in Therapies :
The general population is aging and total joint replacements should not be the only solution for OA. So herein is an actual review of the developments for treating OA with biologics, intended to be useful for the population inside orthopedics who could be called bio-orthopedists, since OA is a molecular homeostasis disbalance between catabolism and anabolism triggered by mechanical stress.
Normal appearance of the hyaline cartilage and the subchondral bone in a fragment of the femoral condyle.
Notes: Presence of blood vessels in the marrow area (A) and lack of them in the cartilage (B).